Product Data Sheet
Ticlopidine-d4
Catalog No. A65354
Ticlopidine-d4 is a stable isotope-labeled form of Ticlopidine, an antithrombotic agent that functions as an allosteric, noncompetitive inhibitor of the enzyme CD39, exhibiting an IC50 of 81.7 μM. Additionally, Ticlopidine-d4 inhibits multiple NTPDase isoenzymes, with IC50 values of 170 μM for NTPDase2 and 149 μM for NTPDase3. It also serves as an inhibitor of cytochrome P450 enzymes CYP2C19, CYP2C9, and CYP3A4, with respective IC50 values of 26.0 μM and 32.3 μM. This reagent is valuable for studying the pharmacodynamics and metabolism of Ticlopidine in biochemical research.
Chemical Information
| Catalog Num | A65354 |
|---|---|
| M. Wt | 267.81 |
| Formula | C14H10D4ClNS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1246817-49-1 |
| Synonyms | PCR 5332-d4 |
| SMILES | ClC(C([2H])=C([2H])C([2H])=C1[2H])=C1CN2CC3=C(SC=C3)CC2 |
Biological Activity
| Description | Ticlopidine-d4 is a stable isotope-labeled form of Ticlopidine, an antithrombotic agent that functions as an allosteric, noncompetitive inhibitor of the enzyme CD39, exhibiting an IC50 of 81.7 μM. Additionally, Ticlopidine-d4 inhibits multiple NTPDase isoenzymes, with IC50 values of 170 μM for NTPDase2 and 149 μM for NTPDase3. It also serves as an inhibitor of cytochrome P450 enzymes CYP2C19, CYP2C9, and CYP3A4, with respective IC50 values of 26.0 μM and 32.3 μM. This reagent is valuable for studying the pharmacodynamics and metabolism of Ticlopidine in biochemical research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
