Product Data Sheet

NFATc1-IN-1

Catalog No. A65365

main product photo
NFATc1-IN-1 is a potent inhibitor of RANKL-induced osteoclast formation, exhibiting an IC50 of 1.57 μM. This compound exerts its anti-osteoclastogenic effects by disrupting the RANKL-mediated nuclear translocation of NFATc1. NFATc1-IN-1 is a valuable tool for research into osteoclastic diseases, providing insights into the regulation of osteoclastogenesis.
Chemical Information
Catalog NumA65365
M. Wt375.11
FormulaC13H8F2INO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1912422-56-0
Synonyms
SMILESOC1=C(C(NC2=C(F)C=C(I)C=C2)=O)C=C(F)C=C1
Biological Activity
DescriptionNFATc1-IN-1 is a potent inhibitor of RANKL-induced osteoclast formation, exhibiting an IC50 of 1.57 μM. This compound exerts its anti-osteoclastogenic effects by disrupting the RANKL-mediated nuclear translocation of NFATc1. NFATc1-IN-1 is a valuable tool for research into osteoclastic diseases, providing insights into the regulation of osteoclastogenesis.
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