Product Data Sheet

mPGES1-IN-6

Catalog No. A65402

main product photo
mPGES1-IN-6 is a potent inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 value of 0.03 μM. By effectively blocking mPGES-1, this compound plays a crucial role in reducing prostaglandin E2 synthesis, making it valuable for studies related to inflammation and pain modulation. mPGES1-IN-6 is suitable for research applications focused on anti-inflammatory drug discovery and the investigation of related signaling pathways.
Chemical Information
Catalog NumA65402
M. Wt386.43
FormulaC21H14N4O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2914158-00-0
Synonyms
SMILESS=C1NN=C(O1)C2=CC=C3NC(C4=CC=C(C=C4)OC5=CC=CC=C5)=NC3=C2
Biological Activity
DescriptionmPGES1-IN-6 is a potent inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 value of 0.03 μM. By effectively blocking mPGES-1, this compound plays a crucial role in reducing prostaglandin E2 synthesis, making it valuable for studies related to inflammation and pain modulation. mPGES1-IN-6 is suitable for research applications focused on anti-inflammatory drug discovery and the investigation of related signaling pathways.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.