Product Data Sheet

BRP-201

Catalog No. A65409

main product photo
BRP-201 is a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), demonstrating an IC50 value of 0.42 μM. This compound exhibits potent anti-inflammatory properties, making it a valuable tool for research in inflammatory diseases. Its specificity for mPGES-1 supports its potential application in the development of next-generation anti-inflammatory therapeutics.
Chemical Information
Catalog NumA65409
M. Wt503.06
FormulaC28H27ClN4OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2227434-74-2
Synonyms
SMILESS=C1OC(C2=CC=C3C(N=C(C(C4=CC=C(CC(C)C)C=C4)C)N3CC5=CC=CC=C5Cl)=C2)=NN1
Biological Activity
DescriptionBRP-201 is a selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1), demonstrating an IC50 value of 0.42 μM. This compound exhibits potent anti-inflammatory properties, making it a valuable tool for research in inflammatory diseases. Its specificity for mPGES-1 supports its potential application in the development of next-generation anti-inflammatory therapeutics.
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