Product Data Sheet
Cryogenine
Catalog No. A65413
Cryogenine is an alkaloid that functions as a selective inhibitor of prostaglandin E synthase, exhibiting significant anti-inflammatory properties. With an IC50 value of 424 μM, Cryogenine effectively attenuates inflammatory responses. In experimental models, administration at doses of 100 mg/kg per day has shown a reduction in paw edema and a decreased mean arthritic index in rats with adjuvant-induced polyarthritis. This makes Cryogenine a valuable reagent for researching inflammation and related disorders.
Chemical Information
| Catalog Num | A65413 |
|---|---|
| M. Wt | 435.51 |
| Formula | C26H29NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 10308-13-1 |
| Synonyms | NSC 272693 |
| SMILES | COC(C=C([C@@]1([H])N(CCCC2)[C@@]2([H])C[C@@](OC3=O)([H])C1)C(C(C=C(/C=C\3)C=C4)=C4O)=C5)=C5OC |
Biological Activity
| Description | Cryogenine is an alkaloid that functions as a selective inhibitor of prostaglandin E synthase, exhibiting significant anti-inflammatory properties. With an IC50 value of 424 μM, Cryogenine effectively attenuates inflammatory responses. In experimental models, administration at doses of 100 mg/kg per day has shown a reduction in paw edema and a decreased mean arthritic index in rats with adjuvant-induced polyarthritis. This makes Cryogenine a valuable reagent for researching inflammation and related disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
