Product Data Sheet
CMB-087229
Catalog No. A65499
CMB-087229 is a specific inhibitor of mutant superoxide dismutase 1 (SOD1) protein aggregation, exhibiting an IC50 of 67 nM. This compound is valuable for research into amyotrophic lateral sclerosis (ALS), providing insights into the pathogenic role of SOD1 aggregates in neurodegenerative diseases. Its application in models of ALS may aid in understanding disease mechanisms and developing potential therapeutic strategies.
Chemical Information
| Catalog Num | A65499 |
|---|---|
| M. Wt | 259.09 |
| Formula | C10H8Cl2N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1227692-67-2 |
| Synonyms | |
| SMILES | O=C1C=C(COC2=CC(Cl)=CC(Cl)=C2)NN1 |
Biological Activity
| Description | CMB-087229 is a specific inhibitor of mutant superoxide dismutase 1 (SOD1) protein aggregation, exhibiting an IC50 of 67 nM. This compound is valuable for research into amyotrophic lateral sclerosis (ALS), providing insights into the pathogenic role of SOD1 aggregates in neurodegenerative diseases. Its application in models of ALS may aid in understanding disease mechanisms and developing potential therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
