Product Data Sheet

SphK2-IN-1

Catalog No. A65530

main product photo
SphK2-IN-1 is a selective inhibitor of sphingosine kinase 2 (SphK2), exhibiting an IC50 of 0.359 μM. This compound plays a crucial role in modulating sphingolipid metabolism, making it valuable in the study of various diseases. SphK2-IN-1 is particularly relevant for research involving cancer, inflammation, and neurological and cardiovascular disorders, providing insights into the therapeutic potential of targeting sphingosine signaling pathways.
Chemical Information
Catalog NumA65530
M. Wt518.92
FormulaC23H22ClF3N8O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2927429-64-7
Synonyms
SMILESN=C(N1CCC[C@H]1C2=NC(C3=CC=C(C=C3)CN4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)=NO2)N.Cl
Biological Activity
DescriptionSphK2-IN-1 is a selective inhibitor of sphingosine kinase 2 (SphK2), exhibiting an IC50 of 0.359 μM. This compound plays a crucial role in modulating sphingolipid metabolism, making it valuable in the study of various diseases. SphK2-IN-1 is particularly relevant for research involving cancer, inflammation, and neurological and cardiovascular disorders, providing insights into the therapeutic potential of targeting sphingosine signaling pathways.
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SHIPPING AND STORAGE
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