Product Data Sheet

SphK2-IN-2

Catalog No. A65533

main product photo
SphK2-IN-2 is a potent and selective inhibitor of sphingosine kinase 2 (SphK2) with an IC50 value of 0.23 μM. This compound demonstrates significant biological activity in regulating sphingolipid metabolism, making it a valuable tool for research applications related to cancer, neurodegenerative diseases, and inflammation. SphK2-IN-2 can aid in elucidating the role of SphK2 in various cellular pathways and the pathophysiology of related disorders.
Chemical Information
Catalog NumA65533
M. Wt468.94
FormulaC21H25ClN10O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2927429-60-3
Synonyms
SMILESCN1C=C(C=N1)C2=CN(N=N2)CC3=CC=C(C=C3)C4=NOC(C[C@@H]5CCCN5C(N)=N)=N4.Cl
Biological Activity
DescriptionSphK2-IN-2 is a potent and selective inhibitor of sphingosine kinase 2 (SphK2) with an IC50 value of 0.23 μM. This compound demonstrates significant biological activity in regulating sphingolipid metabolism, making it a valuable tool for research applications related to cancer, neurodegenerative diseases, and inflammation. SphK2-IN-2 can aid in elucidating the role of SphK2 in various cellular pathways and the pathophysiology of related disorders.
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