Product Data Sheet
cGAMP disodium
Catalog No. A65545
cGAMP disodium, a potent STING activator, functions as an endogenous second messenger that triggers the production of interferons in response to cytosolic DNA. It initiates the stimulator of interferon genes (STING) pathway, resulting in an immune response marked by the production of type I interferons and various immune mediators. This compound is widely used in research focused on innate immunity, cancer immunotherapy, and understanding viral infections.
Chemical Information
| Catalog Num | A65545 |
|---|---|
| M. Wt | 718.37 |
| Formula | C20H22N10Na2O13P2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2407516-83-8 |
| Synonyms | Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium |
| SMILES | [H][C@@]12COP(O[C@]3([C@H]([C@H](N4C=NC5=C(N=CN=C45)N)O[C@@]3(COP(O[C@]1([C@H]([C@H](N6C=NC7=C6N=C(N)NC7=O)O2)O)[H])(O[Na])=O)[H])O)[H])(O[Na])=O |
Biological Activity
| Description | cGAMP disodium, a potent STING activator, functions as an endogenous second messenger that triggers the production of interferons in response to cytosolic DNA. It initiates the stimulator of interferon genes (STING) pathway, resulting in an immune response marked by the production of type I interferons and various immune mediators. This compound is widely used in research focused on innate immunity, cancer immunotherapy, and understanding viral infections. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
