Product Data Sheet

MSA-2 dimer

Catalog No. A65562

main product photo
MSA-2 dimer is a selective, orally active non-nucleotide STING agonist that demonstrates a binding affinity (Kd) of 145 μM. This compound promotes long-term antitumor effects and enhances immunogenic activity by non-covalently interacting with STING in a dimeric form, offering superior permeability compared to cyclic dinucleotides. MSA-2 dimer is particularly valuable for research into cancer immunotherapy and the modulation of innate immune responses.
Chemical Information
Catalog NumA65562
M. Wt568.66
FormulaC29H28O8S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2377881-92-8
Synonyms
SMILESO=C(CCC(C1=CC2=C(C=C(C(CCCC3=CC4=C(C=C3OC)SC(C(CCC(O)=O)=O)=C4)=C2)OC)S1)=O)O
Biological Activity
DescriptionMSA-2 dimer is a selective, orally active non-nucleotide STING agonist that demonstrates a binding affinity (Kd) of 145 μM. This compound promotes long-term antitumor effects and enhances immunogenic activity by non-covalently interacting with STING in a dimeric form, offering superior permeability compared to cyclic dinucleotides. MSA-2 dimer is particularly valuable for research into cancer immunotherapy and the modulation of innate immune responses.
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SHIPPING AND STORAGE
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