Product Data Sheet
diABZI-V/C-Mal
Catalog No. A65576
diABZI-V/C-Mal is a potent STING agonist, exhibiting an EC50 of 314 nM in TH1 dual reporter cells. This compound activates the STING pathway, leading to the subsequent activation of the IRF3 signaling pathway, which plays a critical role in immune response. Additionally, diABZI-V/C-Mal serves as a substrate for Cathepsin B, allowing for the regeneration of diABZI-NH2 through enzymatic cleavage. It is a valuable tool for research in immunology and cancer therapy.
Chemical Information
| Catalog Num | A65576 |
|---|---|
| M. Wt | 1378.49 |
| Formula | C67H83N19O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3035557-55-9 |
| Synonyms | |
| SMILES | O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCNC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C8=CC(C)=NN8CC)=O |
Biological Activity
| Description | diABZI-V/C-Mal is a potent STING agonist, exhibiting an EC50 of 314 nM in TH1 dual reporter cells. This compound activates the STING pathway, leading to the subsequent activation of the IRF3 signaling pathway, which plays a critical role in immune response. Additionally, diABZI-V/C-Mal serves as a substrate for Cathepsin B, allowing for the regeneration of diABZI-NH2 through enzymatic cleavage. It is a valuable tool for research in immunology and cancer therapy. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
