Product Data Sheet
diABZI-Mal
Catalog No. A65577
diABZI-Mal is a STING agonist featuring a maleimide moiety that facilitates the synthesis of conjugates. It effectively activates the cGAS-STING pathway, leading to the production of type I interferons and promoting the maturation of dendritic cells. Additionally, diABZI-Mal enhances CD8+ T cell responses and has demonstrated the ability to inhibit tumor growth, making it a valuable tool in cancer immunotherapy research.
Chemical Information
| Catalog Num | A65577 |
|---|---|
| M. Wt | 1042.15 |
| Formula | C52H63N15O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2763540-24-3 |
| Synonyms | ABM5 |
| SMILES | COC1=C2N(C/C=C/CN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=C3C(OCCCN6CCN(C(CCCCCN7C(C=CC7=O)=O)=O)CC6)=CC(C(N)=O)=C5)C(NC(C8=CC(C)=NN8CC)=O)=NC2=CC(C(N)=O)=C1 |
Biological Activity
| Description | diABZI-Mal is a STING agonist featuring a maleimide moiety that facilitates the synthesis of conjugates. It effectively activates the cGAS-STING pathway, leading to the production of type I interferons and promoting the maturation of dendritic cells. Additionally, diABZI-Mal enhances CD8+ T cell responses and has demonstrated the ability to inhibit tumor growth, making it a valuable tool in cancer immunotherapy research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
