Product Data Sheet
STING agonist-46
Catalog No. A65589
STING agonist-46 is a potent STING agonist that activates the stimulator of interferon genes (STING) signaling pathway, leading to the phosphorylation of TBK1 and IRF3 as well as the secretion of key cytokines such as IFN-β and IP-10. By directly binding to STING, it enhances thermal stability and elicits significant anti-tumor effects in mouse models, including B16F10, CT26, and 4T1. This compound is suitable for research applications focused on cancer immunotherapy and the elucidation of STING-related immune responses.
Chemical Information
| Catalog Num | A65589 |
|---|---|
| M. Wt | 351.42 |
| Formula | C17H21NO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3033532-05-4 |
| Synonyms | |
| SMILES | O=C(CCC(ONC(C)C)=O)C1=CC2=CC(OC)=C(C=C2S1)OC |
Biological Activity
| Description | STING agonist-46 is a potent STING agonist that activates the stimulator of interferon genes (STING) signaling pathway, leading to the phosphorylation of TBK1 and IRF3 as well as the secretion of key cytokines such as IFN-β and IP-10. By directly binding to STING, it enhances thermal stability and elicits significant anti-tumor effects in mouse models, including B16F10, CT26, and 4T1. This compound is suitable for research applications focused on cancer immunotherapy and the elucidation of STING-related immune responses. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
