Product Data Sheet

IACS-8779 disodium

Catalog No. A65597

main product photo
IACS-8779 disodium is a potent stimulator of interferon genes (STING) agonist that elicits a strong activation of the STING signaling pathway. This compound demonstrates significant systemic antitumor efficacy, highlighted by its superior performance in inducing anti-tumor responses in the B16 murine model of melanoma. IACS-8779 disodium is ideal for research applications focused on cancer immunotherapy and the modulation of innate immune responses.
Chemical Information
Catalog NumA65597
M. Wt733.52
FormulaC21H23N9Na2O10P2S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2243079-27-6
Synonyms
SMILESNC1=C(C2=NC=N1)N=CN2[C@@H]3O[C@H]4[C@H]([C@H]3O[P@@](OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C7=C(C=C6)C(N)=NC=N7)O)O[P@@](OC4)(S[Na])=O)(S[Na])=O)O
Biological Activity
DescriptionIACS-8779 disodium is a potent stimulator of interferon genes (STING) agonist that elicits a strong activation of the STING signaling pathway. This compound demonstrates significant systemic antitumor efficacy, highlighted by its superior performance in inducing anti-tumor responses in the B16 murine model of melanoma. IACS-8779 disodium is ideal for research applications focused on cancer immunotherapy and the modulation of innate immune responses.
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SHIPPING AND STORAGE
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