Product Data Sheet
STING agonist-28
Catalog No. A65600
STING agonist-28 is a non-nucleotide small-molecule that serves as a potent agonist for the Stimulator of Interferon Genes (STING) pathway. It activates STING, leading to the phosphorylation of key proteins including TBK1 and IRF3. This compound significantly enhances the production of pro-inflammatory cytokines such as IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells, making it valuable for immunotherapy research. Additionally, STING agonist-28 demonstrates antiviral activity against various SARS-CoV strains, highlighting its potential in antiviral research applications.
Chemical Information
| Catalog Num | A65600 |
|---|---|
| M. Wt | 806.87 |
| Formula | C39H46N14O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2868261-50-9 |
| Synonyms | |
| SMILES | O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCN6CCOCC6)C=C(C(N)=O)C=C5N=C4NC(C7=CC(C)=NN7CC)=O |
Biological Activity
| Description | STING agonist-28 is a non-nucleotide small-molecule that serves as a potent agonist for the Stimulator of Interferon Genes (STING) pathway. It activates STING, leading to the phosphorylation of key proteins including TBK1 and IRF3. This compound significantly enhances the production of pro-inflammatory cytokines such as IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells, making it valuable for immunotherapy research. Additionally, STING agonist-28 demonstrates antiviral activity against various SARS-CoV strains, highlighting its potential in antiviral research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
