Product Data Sheet
STING agonist-44
Catalog No. A65616
STING agonist-44 is a potent and selective agonist targeting the STING pathway. With an EC50 value of 5.68 µM for IRF induction in THP1 cells and 2.212 µM in RAW cells, this compound effectively stimulates the production of type I interferons and pro-inflammatory cytokines, such as CXCL10 and TNFα. STING agonist-44 is a valuable tool for research into cancer immunotherapy and related inflammatory conditions.
Chemical Information
| Catalog Num | A65616 |
|---|---|
| M. Wt | 702.49 |
| Formula | C21H24N10O12P2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3078213-34-7 |
| Synonyms | |
| SMILES | O[C@H]1[C@@H](OP(SC[C@]23[C@@H](O4)[C@@H](OC3)[C@H](N5C=NC6=C5N=CN=C6N)O2)(O)=O)[C@H](N(C=N7)C8=C7C(NC(N)=N8)=O)O[C@@H]1COP4(O)=O |
Biological Activity
| Description | STING agonist-44 is a potent and selective agonist targeting the STING pathway. With an EC50 value of 5.68 µM for IRF induction in THP1 cells and 2.212 µM in RAW cells, this compound effectively stimulates the production of type I interferons and pro-inflammatory cytokines, such as CXCL10 and TNFα. STING agonist-44 is a valuable tool for research into cancer immunotherapy and related inflammatory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
