Product Data Sheet

Tumour-associated MUC1 epitope

Catalog No. A65691

main product photo
Tumour-associated MUC1 epitope is a bioactive peptide targeting the MUC1 mucin, a type I transmembrane glycoprotein characterized by a highly glycosylated extracellular domain composed of repeated 20 amino acid units. This epitope is overexpressed on the surface of various human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma. Its frequent upregulation in cancer cells renders the MUC1 epitope a valuable target for the development of immunotherapeutic strategies, facilitating advancements in cancer treatment research.
Chemical Information
Catalog NumA65691
M. Wt1887.02
FormulaC80H127N25O28
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.129437-45-2
Synonyms
SMILESC(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC(CNC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@@H]4CCCN4)CC(O)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)CCC3)C)=O)CCC2)=O)CO)=O)[C@@H](C)O)=O)C)=O)CCC1)N5[C@H](C(N[C@H](C(N[C@@H](CC6=CN=CN6)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)CO)=O)[C@@H](C)O)=O)[C@@H](C)C)=O)=O)=O)C)=O)CCC5
Biological Activity
DescriptionTumour-associated MUC1 epitope is a bioactive peptide targeting the MUC1 mucin, a type I transmembrane glycoprotein characterized by a highly glycosylated extracellular domain composed of repeated 20 amino acid units. This epitope is overexpressed on the surface of various human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma. Its frequent upregulation in cancer cells renders the MUC1 epitope a valuable target for the development of immunotherapeutic strategies, facilitating advancements in cancer treatment research.
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SHIPPING AND STORAGE
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