Product Data Sheet
LinTT1 peptide
Catalog No. A65700
LinTT1 peptide is a tumor-penetrating peptide that specifically targets the p32 (gC1qR) receptor. This peptide demonstrates enhanced cellular uptake in peritoneal carcinoma (PC) cells, facilitating mitochondrial entry and promoting targeted drug delivery. When conjugated with iron oxide nanoworms, LinTT1 forms a nanocarrier that significantly enhances tumor penetration and targeting in vivo. Additionally, when combined with the pro-apoptotic peptide [D(KLAKLAK)2], LinTT1-functionalized nanocarriers exhibit pronounced tumor suppression in mouse models of peritoneal cancer, highlighting its potential as an effective carrier in cancer research.
Chemical Information
| Catalog Num | A65700 |
|---|---|
| M. Wt | 917.03 |
| Formula | C36H68N16O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2031154-77-3 |
| Synonyms | |
| SMILES | [C@@H](NC([C@H](CCCCN)NC([C@H](C)N)=O)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@@H](C)O)=O)CO)=O)CCCNC(=N)N)=O)C)=O)=O)CCCNC(=N)N |
Biological Activity
| Description | LinTT1 peptide is a tumor-penetrating peptide that specifically targets the p32 (gC1qR) receptor. This peptide demonstrates enhanced cellular uptake in peritoneal carcinoma (PC) cells, facilitating mitochondrial entry and promoting targeted drug delivery. When conjugated with iron oxide nanoworms, LinTT1 forms a nanocarrier that significantly enhances tumor penetration and targeting in vivo. Additionally, when combined with the pro-apoptotic peptide [D(KLAKLAK)2], LinTT1-functionalized nanocarriers exhibit pronounced tumor suppression in mouse models of peritoneal cancer, highlighting its potential as an effective carrier in cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
