Product Data Sheet
GW284543 hydrochloride
Catalog No. A65814
GW284543 hydrochloride is a selective inhibitor of MEK5, a key regulator in the MAPK signaling pathway. This compound effectively reduces phosphorylated ERK5 (pERK5) levels while decreasing the endogenous MYC protein. It is valuable for research applications investigating cellular signaling pathways, tumor biology, and potential therapeutic targets in various cancers.
Chemical Information
| Catalog Num | A65814 |
|---|---|
| M. Wt | 408.88 |
| Formula | C23H21ClN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 179246-08-3 |
| Synonyms | UNC10225170 hydrochloride |
| SMILES | COC1=CC2=C(NC3=CC(OC4=CC=CC=C4)=CC=C3)C=CN=C2C=C1OC.Cl |
Biological Activity
| Description | GW284543 hydrochloride is a selective inhibitor of MEK5, a key regulator in the MAPK signaling pathway. This compound effectively reduces phosphorylated ERK5 (pERK5) levels while decreasing the endogenous MYC protein. It is valuable for research applications investigating cellular signaling pathways, tumor biology, and potential therapeutic targets in various cancers. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
