Product Data Sheet
Pimasertib hydrochloride
Catalog No. A65818
Pimasertib hydrochloride is a selective allosteric inhibitor of MEK1/2, functioning through non-competitive inhibition of ATP-binding. This compound is notable for its ability to effectively block the MAPK signaling pathway, which is crucial in various cancers. Pimasertib is utilized in research focused on cancer therapeutics and cell signaling mechanisms, making it a valuable tool for studying tumor progression and drug resistance.
Chemical Information
| Catalog Num | A65818 |
|---|---|
| M. Wt | 467.66 |
| Formula | C15H16ClFIN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1236361-78-6 |
| Synonyms | AS703026 hydrochloride; MSC1936369B hydrochloride |
| SMILES | OC[C@@H](O)CNC(C1=CC=NC=C1NC2=C(C=C(C=C2)I)F)=O.Cl |
Biological Activity
| Description | Pimasertib hydrochloride is a selective allosteric inhibitor of MEK1/2, functioning through non-competitive inhibition of ATP-binding. This compound is notable for its ability to effectively block the MAPK signaling pathway, which is crucial in various cancers. Pimasertib is utilized in research focused on cancer therapeutics and cell signaling mechanisms, making it a valuable tool for studying tumor progression and drug resistance. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
