Product Data Sheet
Polfurmetinib hydrate
Catalog No. A65822
Polfurmetinib hydrate is a potent MEK inhibitor, exhibiting an IC50 of 2 nM against A375 melanoma cells. This compound effectively hinders the MEK signaling pathway, making it a valuable tool for studies of cancer biology and therapeutic development. Its selective inhibition of MEK allows for insights into cellular signaling mechanisms and contributes to research on targeted cancer therapies.
Chemical Information
| Catalog Num | A65822 |
|---|---|
| M. Wt | 411.45 |
| Formula | C18H22FN3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2845153-35-5 |
| Synonyms | MEK-IN-6 hydrate |
| SMILES | O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC.O |
Biological Activity
| Description | Polfurmetinib hydrate is a potent MEK inhibitor, exhibiting an IC50 of 2 nM against A375 melanoma cells. This compound effectively hinders the MEK signaling pathway, making it a valuable tool for studies of cancer biology and therapeutic development. Its selective inhibition of MEK allows for insights into cellular signaling mechanisms and contributes to research on targeted cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
