Product Data Sheet
L-Phenylalanine-d2
Catalog No. A66034
L-Phenylalanine-d2 is a deuterium-labeled form of the essential amino acid L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid). It serves as a stable isotope and acts as an antagonist of the α2δ subunit of voltage-dependent calcium channels, with a Ki of 980 nM. Additionally, L-Phenylalanine-d2 competitively inhibits glycine- and glutamate-binding sites on both N-methyl-D-aspartate receptors (NMDARs) and non-NMDARs, demonstrating a Ki of 573 μM. This reagent is valuable for applications in biochemical research, including metabolic studies and tracer experiments.
Chemical Information
| Catalog Num | A66034 |
|---|---|
| M. Wt | 167.20 |
| Formula | C9H9D2NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 221346-31-2 |
| Synonyms | (S)-2-Amino-3-phenylpropionic acid-d2 |
| SMILES | N[C@@H](C([2H])([2H])C1=CC=CC=C1)C(O)=O |
Biological Activity
| Description | L-Phenylalanine-d2 is a deuterium-labeled form of the essential amino acid L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid). It serves as a stable isotope and acts as an antagonist of the α2δ subunit of voltage-dependent calcium channels, with a Ki of 980 nM. Additionally, L-Phenylalanine-d2 competitively inhibits glycine- and glutamate-binding sites on both N-methyl-D-aspartate receptors (NMDARs) and non-NMDARs, demonstrating a Ki of 573 μM. This reagent is valuable for applications in biochemical research, including metabolic studies and tracer experiments. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
