Product Data Sheet

L-Phenylalanine-13C9,15N

Catalog No. A66037

main product photo
L-Phenylalanine-13C9,15N is a stable isotope-labeled version of the essential amino acid L-Phenylalanine, featuring carbon-13 and nitrogen-15 isotopes. This compound serves as an α2δ subunit antagonist for voltage-dependent Ca²⁺ channels, exhibiting a Ki of 980 nM. Additionally, L-Phenylalanine acts as a competitive antagonist at the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs), with a KB of 573 μM. Its applications extend to the fields of metabolic studies, tracer studies in amino acid metabolism, and the development of food flavors and pharmaceuticals.
Chemical Information
Catalog NumA66037
M. Wt175.12
Formula13C9H1115NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.878339-23-2
Synonyms(S)-2-Amino-3-phenylpropionic acid-13C9,15N
SMILESO[13C]([13C@@H]([13CH2][13C]1=[13CH][13CH]=[13CH][13CH]=[13CH]1)[15NH2])=O
Biological Activity
DescriptionL-Phenylalanine-13C9,15N is a stable isotope-labeled version of the essential amino acid L-Phenylalanine, featuring carbon-13 and nitrogen-15 isotopes. This compound serves as an α2δ subunit antagonist for voltage-dependent Ca²⁺ channels, exhibiting a Ki of 980 nM. Additionally, L-Phenylalanine acts as a competitive antagonist at the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs), with a KB of 573 μM. Its applications extend to the fields of metabolic studies, tracer studies in amino acid metabolism, and the development of food flavors and pharmaceuticals.
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SHIPPING AND STORAGE
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