Product Data Sheet
3-(3-Hydroxyphenyl)propionic acid
Catalog No. A66109
3-(3-Hydroxyphenyl)propionic acid (3HPPA) functions as an endothelium-dependent promoter of nitric oxide (NO) release and an activator of endothelial nitric oxide synthase (eNOS). This compound facilitates vascular smooth muscle relaxation by enhancing NO synthesis in endothelial cells, leading to vasodilation and decreased peripheral vascular resistance. In studies, 3HPPA has shown a dose-dependent ability to lower systolic and diastolic blood pressure in spontaneously hypertensive rats without affecting cardiac contractility or heart rate. Its antihypertensive and vascular protective properties make it a valuable reagent for investigating cardiovascular disease prevention and treatment.
Chemical Information
| Catalog Num | A66109 |
|---|---|
| M. Wt | 166.18 |
| Formula | C9H10O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 621-54-5 |
| Synonyms | |
| SMILES | O=C(O)CCC1=CC=CC(O)=C1 |
Biological Activity
| Description | 3-(3-Hydroxyphenyl)propionic acid (3HPPA) functions as an endothelium-dependent promoter of nitric oxide (NO) release and an activator of endothelial nitric oxide synthase (eNOS). This compound facilitates vascular smooth muscle relaxation by enhancing NO synthesis in endothelial cells, leading to vasodilation and decreased peripheral vascular resistance. In studies, 3HPPA has shown a dose-dependent ability to lower systolic and diastolic blood pressure in spontaneously hypertensive rats without affecting cardiac contractility or heart rate. Its antihypertensive and vascular protective properties make it a valuable reagent for investigating cardiovascular disease prevention and treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
