Product Data Sheet
TAT-CBD3A6K
Catalog No. A66117
TAT-CBD3A6K is a modified TAT-CBD3 peptide that primarily targets voltage-dependent calcium channels. This compound effectively reduces T- and R-type calcium currents in dorsal root ganglion (DRG) neurons, demonstrating notable anti-nociceptive properties. TAT-CBD3A6K has been shown to mitigate pain in a model of AIDS-induced peripheral neuropathy by preventing the CRMP-2-mediated enhancement of T- and R-type calcium channel activity, making it a valuable tool for studying pain mechanisms and peripheral neuropathy interventions.
Chemical Information
| Catalog Num | A66117 |
|---|---|
| M. Wt | 3249.83 |
| Formula | C137H250N60O32 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1505463-57-9 |
| Synonyms | |
| SMILES | C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCCNC(=N)N)(=O)[C@H]1N(C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)C(C)C)=O)CCC1 |
Biological Activity
| Description | TAT-CBD3A6K is a modified TAT-CBD3 peptide that primarily targets voltage-dependent calcium channels. This compound effectively reduces T- and R-type calcium currents in dorsal root ganglion (DRG) neurons, demonstrating notable anti-nociceptive properties. TAT-CBD3A6K has been shown to mitigate pain in a model of AIDS-induced peripheral neuropathy by preventing the CRMP-2-mediated enhancement of T- and R-type calcium channel activity, making it a valuable tool for studying pain mechanisms and peripheral neuropathy interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
