Product Data Sheet

Amlodipine-d4

Catalog No. A66119

main product photo
Amlodipine-d4 is a deuterium-labeled derivative of Amlodipine, a dihydropyridine calcium channel blocker and antianginal agent. This compound selectively inhibits voltage-dependent L-type calcium channels, leading to reduced calcium influx. Amlodipine-d4 is primarily utilized in pharmacokinetics studies and metabolic research to investigate the pharmacological effects of Amlodipine in conditions such as hypertension and cancer.
Chemical Information
Catalog NumA66119
M. Wt412.90
FormulaC20H21D4ClN2O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1185246-14-3
Synonyms
SMILESCCOC(C1=C(COC([2H])([2H])C([2H])([2H])N)NC(C)=C(C(OC)=O)C1C2=C(C=CC=C2)Cl)=O
Biological Activity
DescriptionAmlodipine-d4 is a deuterium-labeled derivative of Amlodipine, a dihydropyridine calcium channel blocker and antianginal agent. This compound selectively inhibits voltage-dependent L-type calcium channels, leading to reduced calcium influx. Amlodipine-d4 is primarily utilized in pharmacokinetics studies and metabolic research to investigate the pharmacological effects of Amlodipine in conditions such as hypertension and cancer.
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