Product Data Sheet

Calcium Channel antagonist 6

Catalog No. A66169

main product photo
Calcium Channel Antagonist 6 (Compound 328) selectively inhibits the voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. This compound effectively blocks neuron depolarization-induced Ca2+ influx, making it a valuable tool for investigating mechanisms underlying neuropathic pain. Its specificity and potency position it as a promising candidate for further research in pain-related studies.
Chemical Information
Catalog NumA66169
M. Wt451.54
FormulaC21H29N3O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.687568-35-0
Synonyms
SMILESO=C(N1CCN(CC1)C(C2=C(C)C3=C(C=CC(S(=O)(N(CC)CC)=O)=C3)O2)=O)OCC
Biological Activity
DescriptionCalcium Channel Antagonist 6 (Compound 328) selectively inhibits the voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. This compound effectively blocks neuron depolarization-induced Ca2+ influx, making it a valuable tool for investigating mechanisms underlying neuropathic pain. Its specificity and potency position it as a promising candidate for further research in pain-related studies.
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