Product Data Sheet
Niguldipine (free base)
Catalog No. A66200
Niguldipine is a calcium channel blocker that primarily targets voltage-gated calcium channels to modulate cardiovascular function. It effectively reduces both systolic and diastolic blood pressure while simultaneously increasing heart rate and cardiac output. Additionally, Niguldipine promotes dose-dependent increases in coronary blood flow and transiently enhances renal and femoral artery perfusion. Its influence on myocardial metabolism is minimal, making it a valuable compound for cardiovascular research applications.
Chemical Information
| Catalog Num | A66200 |
|---|---|
| M. Wt | 609.71 |
| Formula | C36H39N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 102993-22-6 |
| Synonyms | |
| SMILES | O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCCN3CCC(C4=CC=CC=C4)(C5=CC=CC=C5)CC3 |
Biological Activity
| Description | Niguldipine is a calcium channel blocker that primarily targets voltage-gated calcium channels to modulate cardiovascular function. It effectively reduces both systolic and diastolic blood pressure while simultaneously increasing heart rate and cardiac output. Additionally, Niguldipine promotes dose-dependent increases in coronary blood flow and transiently enhances renal and femoral artery perfusion. Its influence on myocardial metabolism is minimal, making it a valuable compound for cardiovascular research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
