Product Data Sheet
dl-Tetrandrine
Catalog No. A66216
dl-Tetrandrine is a potent calcium channel blocker that inhibits voltage-dependent calcium channels, selectively blocking Ca2+ influx with an IC50 ranging from 1-10 μM. This compound exhibits significant anti-inflammatory, immunosuppressive, and anti-arrhythmic properties by preventing intracellular calcium overload. dl-Tetrandrine is of particular interest in research related to autoimmune diseases, including rheumatoid arthritis, cardiovascular disorders, and the reversal of multidrug resistance in tumor cells.
Chemical Information
| Catalog Num | A66216 |
|---|---|
| M. Wt | 622.75 |
| Formula | C38H42N2O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 23495-89-8 |
| Synonyms | |
| SMILES | COC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CCN6C)OC)C=C5)=C4 |
Biological Activity
| Description | dl-Tetrandrine is a potent calcium channel blocker that inhibits voltage-dependent calcium channels, selectively blocking Ca2+ influx with an IC50 ranging from 1-10 μM. This compound exhibits significant anti-inflammatory, immunosuppressive, and anti-arrhythmic properties by preventing intracellular calcium overload. dl-Tetrandrine is of particular interest in research related to autoimmune diseases, including rheumatoid arthritis, cardiovascular disorders, and the reversal of multidrug resistance in tumor cells. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
