Product Data Sheet
Cimicifugic acid D
Catalog No. A66221
Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that acts as a vasodilator, promoting endothelium-independent relaxation in precontracted rat aortic strips. Its primary mechanism involves the inhibition of extracellular Ca2+ influx through receptor-operated calcium channels (ROC), effectively countering norepinephrine-induced contractions. Notably, Cimicifugic acid D does not interfere with voltage-dependent calcium channels or K+-induced contractions, making it a valuable tool for studying vascular smooth muscle responses and calcium signaling pathways.
Chemical Information
| Catalog Num | A66221 |
|---|---|
| M. Wt | 418.35 |
| Formula | C20H18O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 219986-51-3 |
| Synonyms | 2-Caffeoylpiscidic acid |
| SMILES | OC(C=C1)=CC=C1C[C@@](C(O)=O)(O)[C@@H](C(O)=O)OC(/C=C/C2=CC(O)=C(C=C2)O)=O |
Biological Activity
| Description | Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that acts as a vasodilator, promoting endothelium-independent relaxation in precontracted rat aortic strips. Its primary mechanism involves the inhibition of extracellular Ca2+ influx through receptor-operated calcium channels (ROC), effectively countering norepinephrine-induced contractions. Notably, Cimicifugic acid D does not interfere with voltage-dependent calcium channels or K+-induced contractions, making it a valuable tool for studying vascular smooth muscle responses and calcium signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
