Product Data Sheet
Ranolazine-d5
Catalog No. A66241
Ranolazine-d5 is a deuterium-labeled analogue of Ranolazine, which primarily targets the late phase of inward sodium current (INa) and potassium channels (IKr), exhibiting IC50 values of 6 μM and 12 μM, respectively. This compound functions as an anti-anginal agent by alleviating myocardial ischemia without influencing heart rate or blood pressure. Additionally, Ranolazine-d5 serves as a partial inhibitor of fatty acid oxidation (FAO), making it valuable for research in cardiovascular pharmacology and metabolic studies.
Chemical Information
| Catalog Num | A66241 |
|---|---|
| M. Wt | 432.57 |
| Formula | C24H28D5N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1092804-87-9 |
| Synonyms | CVT 303-d5; RS 43285-003-d5 |
| SMILES | CC(C=CC=C1C)=C1NC(CN(CC2)CCN2C([2H])([2H])C(O)([2H])C([2H])([2H])OC3=C(C=CC=C3)OC)=O |
Biological Activity
| Description | Ranolazine-d5 is a deuterium-labeled analogue of Ranolazine, which primarily targets the late phase of inward sodium current (INa) and potassium channels (IKr), exhibiting IC50 values of 6 μM and 12 μM, respectively. This compound functions as an anti-anginal agent by alleviating myocardial ischemia without influencing heart rate or blood pressure. Additionally, Ranolazine-d5 serves as a partial inhibitor of fatty acid oxidation (FAO), making it valuable for research in cardiovascular pharmacology and metabolic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
