Product Data Sheet
TTA-A8
Catalog No. A66282
TTA-A8 is a potent T-type calcium channel antagonist, demonstrating an IC50 value of 31.3 nM in the FLIPR depolarization assay. This compound exhibits favorable pharmacokinetic properties, making it an ideal candidate for research applications focused on epilepsy and sleep disorders. Its short-acting profile allows for detailed studies into the physiological roles of T-type calcium channels in related conditions.
Chemical Information
| Catalog Num | A66282 |
|---|---|
| M. Wt | 430.42 |
| Formula | C22H21F3N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1146395-46-1 |
| Synonyms | |
| SMILES | CC1=NC=CN=C1C2=CC=C(C=C2)CC(N[C@@H](C3=CC=C(C=N3)OCC(F)(F)F)C)=O |
Biological Activity
| Description | TTA-A8 is a potent T-type calcium channel antagonist, demonstrating an IC50 value of 31.3 nM in the FLIPR depolarization assay. This compound exhibits favorable pharmacokinetic properties, making it an ideal candidate for research applications focused on epilepsy and sleep disorders. Its short-acting profile allows for detailed studies into the physiological roles of T-type calcium channels in related conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
