Product Data Sheet
Lnd 796
Catalog No. A66316
LND 796 is a calcium channel agonist with positive inotropic effects reminiscent of digitalis. It demonstrates a concentration-dependent increase in contractility in guinea pig papillary muscles, enhancing both contraction components and slow action potential amplitude, particularly in partially potassium-depolarized conditions. The mechanism of action involves increased calcium influx through calcium channels and inhibition of sodium-potassium ATPase. Due to its unique profile, LND 796 may have potential applications in the treatment of congestive heart failure.
Chemical Information
| Catalog Num | A66316 |
|---|---|
| M. Wt | 495.65 |
| Formula | C27H45NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 118549-42-1 |
| Synonyms | |
| SMILES | N[C@@]([C@@]12C)(CC[C@@H]1C(OC)=O)[C@@](CC[C@]3([H])C[C@H]4O[C@H](O[C@H]5C)[C@@H]([C@@H]([C@H]5O)O)O)([H])[C@@](CC2)([H])[C@]3(CC4)C |
Biological Activity
| Description | LND 796 is a calcium channel agonist with positive inotropic effects reminiscent of digitalis. It demonstrates a concentration-dependent increase in contractility in guinea pig papillary muscles, enhancing both contraction components and slow action potential amplitude, particularly in partially potassium-depolarized conditions. The mechanism of action involves increased calcium influx through calcium channels and inhibition of sodium-potassium ATPase. Due to its unique profile, LND 796 may have potential applications in the treatment of congestive heart failure. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
