Product Data Sheet
JTV-519 fumarate
Catalog No. A66340
JTV-519 fumarate is a Ca2+-dependent blocker of the sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA), functioning as a partial agonist for ryanodine receptors in striated muscle. This compound exhibits cardioprotective properties and demonstrates significant antiarrhythmic activity, making it valuable for research on cardiac function and arrhythmias. Its unique mechanism highlights its potential in studying calcium handling and related cardiac pathologies.
Chemical Information
| Catalog Num | A66340 |
|---|---|
| M. Wt | 540.67 |
| Formula | C29H36N2O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1883549-36-7 |
| Synonyms | K201 fumarate |
| SMILES | COC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1.O=C(O)/C=C/C(O)=O |
Biological Activity
| Description | JTV-519 fumarate is a Ca2+-dependent blocker of the sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA), functioning as a partial agonist for ryanodine receptors in striated muscle. This compound exhibits cardioprotective properties and demonstrates significant antiarrhythmic activity, making it valuable for research on cardiac function and arrhythmias. Its unique mechanism highlights its potential in studying calcium handling and related cardiac pathologies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
