Product Data Sheet
S-312-d
Catalog No. A66341
S-312-d is a calcium channel antagonist that exhibits protective effects against ischemic acute renal failure. Administered intravenously at doses of 0.01-0.1 mg/kg body weight prior to ischemia, S-312-d demonstrates a dose-dependent reduction in ischemia-induced renal injury, enhances survival rates in ischemic models, and mitigates renal cortical edema as well as elevated renal tissue calcium levels. This compound is valuable for research into renal protection mechanisms and the pathophysiology of acute kidney injury.
Chemical Information
| Catalog Num | A66341 |
|---|---|
| M. Wt | 386.46 |
| Formula | C20H22N2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 120056-57-7 |
| Synonyms | S-(+)-S-312-d |
| SMILES | CC(CC1=CSC2=C1[C@H](C(C(OC)=O)=C(N2)C)C3=CC([N+]([O-])=O)=CC=C3)C |
Biological Activity
| Description | S-312-d is a calcium channel antagonist that exhibits protective effects against ischemic acute renal failure. Administered intravenously at doses of 0.01-0.1 mg/kg body weight prior to ischemia, S-312-d demonstrates a dose-dependent reduction in ischemia-induced renal injury, enhances survival rates in ischemic models, and mitigates renal cortical edema as well as elevated renal tissue calcium levels. This compound is valuable for research into renal protection mechanisms and the pathophysiology of acute kidney injury. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
