Product Data Sheet

Sarafotoxin S6d

Catalog No. A66342

main product photo
Sarafotoxin S6d is a polypeptide toxin derived from the venom of the Israeli sand boa constrictor, known for its cardiovascular effects. This compound induces significant electrocardiogram (ECG) alterations, including myocardial ischemia and hyperkalemia, while also promoting robust extracellular calcium-dependent vasoconstriction in rat aorta and positive inotropic effects in rat atria. Sarafotoxin S6d is valuable in the investigation of cardiovascular pathologies and related physiological mechanisms.
Chemical Information
Catalog NumA66342
M. Wt2591.98
FormulaC112H163N27O34S5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1446991-36-1
SynonymsSTX-b
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H](CC(C)C)NC(=O)[C@]5(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@](NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@@H](N)CSSC2)[H])(CSSC5)[H])[H])[H])=O)CCC(N)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=6C=7C(NC6)=CC=CC7
Biological Activity
DescriptionSarafotoxin S6d is a polypeptide toxin derived from the venom of the Israeli sand boa constrictor, known for its cardiovascular effects. This compound induces significant electrocardiogram (ECG) alterations, including myocardial ischemia and hyperkalemia, while also promoting robust extracellular calcium-dependent vasoconstriction in rat aorta and positive inotropic effects in rat atria. Sarafotoxin S6d is valuable in the investigation of cardiovascular pathologies and related physiological mechanisms.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.