Product Data Sheet

PD-151307

Catalog No. A66374

main product photo
PD-151307 is an N-type calcium channel antagonist that effectively inhibits calcium influx in neuroblastoma cells, demonstrated by an IC50 of 0.32 µM in IMR-32 human neuroblastoma cells. This compound is pertinent for research applications in cancer therapy, anticonvulsant studies, and models of neuropathic pain, making it a valuable tool for investigating calcium channel modulation in various neurological conditions.
Chemical Information
Catalog NumA66374
M. Wt565.74
FormulaC33H47N3O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.225925-12-2
Synonyms
SMILESO=C([C@@H](NC([C@@H](NC(N1CCCCCC1)=O)CC(C)C)=O)CC2=CC=C(C=C2)OCC3=CC=CC=C3)OC(C)(C)C
Biological Activity
DescriptionPD-151307 is an N-type calcium channel antagonist that effectively inhibits calcium influx in neuroblastoma cells, demonstrated by an IC50 of 0.32 µM in IMR-32 human neuroblastoma cells. This compound is pertinent for research applications in cancer therapy, anticonvulsant studies, and models of neuropathic pain, making it a valuable tool for investigating calcium channel modulation in various neurological conditions.
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