Product Data Sheet

SR33805 analog

Catalog No. A66379

main product photo
SR33805 analog is an orally active calcium channel blocker that effectively inhibits the proliferation of smooth muscle cells. By blocking calcium channels, it reduces calcium uptake, thereby attenuating proliferation induced by serum, platelet-derived growth factor, and basic fibroblast growth factor. Notably, SR33805 analog has demonstrated a significant reduction in intimal thickening following endothelial injury in animal models. This compound holds promise for research into cardiovascular diseases, particularly early atherosclerosis.
Chemical Information
Catalog NumA66379
M. Wt564.74
FormulaC32H40N2O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.121346-32-5
Synonyms
SMILESO=S(C1=CC=C(C=C1)OCCCN(CCC2=CC=C(C(OC)=C2)OC)C)(C(N3C)=C(C4=C3C=CC=C4)C(C)C)=O
Biological Activity
DescriptionSR33805 analog is an orally active calcium channel blocker that effectively inhibits the proliferation of smooth muscle cells. By blocking calcium channels, it reduces calcium uptake, thereby attenuating proliferation induced by serum, platelet-derived growth factor, and basic fibroblast growth factor. Notably, SR33805 analog has demonstrated a significant reduction in intimal thickening following endothelial injury in animal models. This compound holds promise for research into cardiovascular diseases, particularly early atherosclerosis.
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SHIPPING AND STORAGE
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