Product Data Sheet

NJH-2-057

Catalog No. A66456

main product photo
NJH-2-057 is a CFTR modulator that functions as an EN523 OTUB1 recruiter. It is designed to enhance the activity of the ΔF508-CFTR mutant protein, which is associated with cystic fibrosis. This compound has potential applications in studying CFTR modulation and offers insights into therapeutic strategies for cystic fibrosis treatment.
Chemical Information
Catalog NumA66456
M. Wt810.84
FormulaC43H44F2N6O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2858812-70-9
Synonyms
SMILESO=C(N1CC(N(CC1)C2=CC=C(CCC(NCCCCCNC(C3=CC=CC(C4=NC(NC(C5(CC5)C6=CC=C7OC(F)(OC7=C6)F)=O)=CC=C4C)=C3)=O)=O)O2)=O)C=C
Biological Activity
DescriptionNJH-2-057 is a CFTR modulator that functions as an EN523 OTUB1 recruiter. It is designed to enhance the activity of the ΔF508-CFTR mutant protein, which is associated with cystic fibrosis. This compound has potential applications in studying CFTR modulation and offers insights into therapeutic strategies for cystic fibrosis treatment.
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SHIPPING AND STORAGE
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