Product Data Sheet
IDOR-4
Catalog No. A66461
IDOR-4 is a type IV CFTR corrector that enhances the trafficking of the F508del-CFTR mutant to the cell surface. This compound is crucial for restoring functional chloride ion transport in cystic fibrosis research and can be utilized to study the dynamics of CFTR correction mechanisms in cellular models. Its application may contribute to the development of therapeutic strategies for patients with cystic fibrosis caused by the F508del mutation.
Chemical Information
| Catalog Num | A66461 |
|---|---|
| M. Wt | 916.95 |
| Formula | C44H51F3N12O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2839901-24-3 |
| Synonyms | |
| SMILES | CC1=C2N=CC=CC2=C3C(N[C@@H](CC(N([C@H](C(N([C@@H](C(N[C@@H](COC3=C1)CC4=CC=CC=C4)=O)CC5=NC(C(F)(F)F)=NO5)C)=O)CC(C)C)C)=O)C(NCCN6N=NC(C7CC7)=N6)=O)=O |
Biological Activity
| Description | IDOR-4 is a type IV CFTR corrector that enhances the trafficking of the F508del-CFTR mutant to the cell surface. This compound is crucial for restoring functional chloride ion transport in cystic fibrosis research and can be utilized to study the dynamics of CFTR correction mechanisms in cellular models. Its application may contribute to the development of therapeutic strategies for patients with cystic fibrosis caused by the F508del mutation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
