Product Data Sheet

Galicaftor

Catalog No. A66463

main product photo
Galicaftor is a potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It plays a crucial role in restoring the function of the CFTR protein, which is often impaired in cystic fibrosis patients. This compound is primarily utilized in research focusing on cystic fibrosis therapies and the modulation of ion transport involved in this condition.
Chemical Information
Catalog NumA66463
M. Wt559.46
FormulaC28H21F4NO7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1918143-53-9
SynonymsABBV-2222; GLPG-2222
SMILESO=C(O)C1=CC=C([C@H]2C[C@@H](NC(C3(C4=CC=C(OC(F)(F)O5)C5=C4)CC3)=O)C6=CC=C(OC(F)F)C=C6O2)C=C1
Biological Activity
DescriptionGalicaftor is a potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It plays a crucial role in restoring the function of the CFTR protein, which is often impaired in cystic fibrosis patients. This compound is primarily utilized in research focusing on cystic fibrosis therapies and the modulation of ion transport involved in this condition.
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.