Product Data Sheet

CFTR activator 1

Catalog No. A66466

main product photo
CFTR activator 1 is a potent and selective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) channel, exhibiting an EC50 of 23 nM. This compound effectively enhances CFTR function and is applicable in research related to dry eye disease treatment. Its ability to promote chloride ion transport makes it a valuable tool for investigating therapeutic strategies in CFTR-related pathologies.
Chemical Information
Catalog NumA66466
M. Wt485.53
FormulaC27H27N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2768261-09-0
Synonyms
SMILESO=C(N1C[C@@H](N(CC1)C(C2=CC=CC=C2)=O)C)C3=NN4C(C5=CC(OC)=C(C=C5)OC)=CC=NC4=C3
Biological Activity
DescriptionCFTR activator 1 is a potent and selective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) channel, exhibiting an EC50 of 23 nM. This compound effectively enhances CFTR function and is applicable in research related to dry eye disease treatment. Its ability to promote chloride ion transport makes it a valuable tool for investigating therapeutic strategies in CFTR-related pathologies.
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