Product Data Sheet
VRT-325
Catalog No. A66471
VRT-325 is a small molecule designed to target the cystic fibrosis transmembrane conductance regulator (CFTR), specifically addressing the ΔF508 mutation associated with cystic fibrosis. This compound promotes the efflux of ΔF508-CFTR from the endoplasmic reticulum, thereby restoring chloride transport in epithelial cells derived from CF patients. VRT-325 is valuable for research into therapeutic strategies aimed at correcting CFTR function and enhancing epithelial ion transport in cystic fibrosis.
Chemical Information
| Catalog Num | A66471 |
|---|---|
| M. Wt | 510.65 |
| Formula | C27H34N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 815592-21-3 |
| Synonyms | |
| SMILES | CC(N1CCN(CC1)S(=O)(C2=CC=C(C=C2)OC)=O)C3=NC(OC4CCCCC4)=C5C=CC=CC5=N3 |
Biological Activity
| Description | VRT-325 is a small molecule designed to target the cystic fibrosis transmembrane conductance regulator (CFTR), specifically addressing the ΔF508 mutation associated with cystic fibrosis. This compound promotes the efflux of ΔF508-CFTR from the endoplasmic reticulum, thereby restoring chloride transport in epithelial cells derived from CF patients. VRT-325 is valuable for research into therapeutic strategies aimed at correcting CFTR function and enhancing epithelial ion transport in cystic fibrosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
