Product Data Sheet
CFTR corrector 15
Catalog No. A66476
CFTR Corrector 15 (Compound 4172) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), specifically designed to repair the folding defect associated with the F508del mutation when used in conjunction with VX-809. This compound is valuable in the research of cystic fibrosis disease, providing insights into therapeutic strategies for restoring proper CFTR function and improving chloride ion transport in epithelial cells. Researchers can utilize CFTR Corrector 15 to advance studies investigating the molecular pathophysiology of cystic fibrosis and the effectiveness of combined drug therapies.
Chemical Information
| Catalog Num | A66476 |
|---|---|
| M. Wt | 479.98 |
| Formula | C24H22ClN5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1170387-92-4 |
| Synonyms | |
| SMILES | CC1=CC(NC(N2N=C(C=C2NC(C3(CCCC3)C4=CC=C(C=C4)Cl)=O)C5=CC=CS5)=N1)=O |
Biological Activity
| Description | CFTR Corrector 15 (Compound 4172) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), specifically designed to repair the folding defect associated with the F508del mutation when used in conjunction with VX-809. This compound is valuable in the research of cystic fibrosis disease, providing insights into therapeutic strategies for restoring proper CFTR function and improving chloride ion transport in epithelial cells. Researchers can utilize CFTR Corrector 15 to advance studies investigating the molecular pathophysiology of cystic fibrosis and the effectiveness of combined drug therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
