Product Data Sheet

CFTR corrector 8

Catalog No. A66477

main product photo
CFTR Corrector 8 is a potent modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It enhances the function of misfolded CFTR mutants, thereby improving chloride transport across epithelial cell membranes. This compound is valuable for research applications focused on cystic fibrosis and related therapies, facilitating investigations into drug efficacy and cellular rescue mechanisms.
Chemical Information
Catalog NumA66477
M. Wt539.52
FormulaC29H27F2NO7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1918142-35-4
Synonyms
SMILESCOC(C=C1[C@H](C2)OC3=CC(OC)=CC=C3[C@H]2NC(C4(C5=CC=C(OC(F)(O6)F)C6=C5)CC4)=O)=C(C=C1)OC
Biological Activity
DescriptionCFTR Corrector 8 is a potent modulator of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. It enhances the function of misfolded CFTR mutants, thereby improving chloride transport across epithelial cell membranes. This compound is valuable for research applications focused on cystic fibrosis and related therapies, facilitating investigations into drug efficacy and cellular rescue mechanisms.
RETURN POLICY
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.