Product Data Sheet
Corr4A
Catalog No. A66482
Corr4A is a chemical corrector that targets the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the surface expression of the ΔF508 CFTR mutant by facilitating its proper folding and trafficking to the plasma membrane. This compound demonstrates significant potential for improving the stability and function of the rescued protein, making it valuable for research focused on cystic fibrosis and related therapies.
Chemical Information
| Catalog Num | A66482 |
|---|---|
| M. Wt | 456.97 |
| Formula | C21H17ClN4O2S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 421580-53-2 |
| Synonyms | |
| SMILES | O=C(NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1)C4=CC=CC=C4 |
Biological Activity
| Description | Corr4A is a chemical corrector that targets the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the surface expression of the ΔF508 CFTR mutant by facilitating its proper folding and trafficking to the plasma membrane. This compound demonstrates significant potential for improving the stability and function of the rescued protein, making it valuable for research focused on cystic fibrosis and related therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
