Product Data Sheet
Bamocaftor potassium
Catalog No. A66501
Bamocaftor potassium is a CFTR corrector that targets the cystic fibrosis transmembrane conductance regulator (CFTR) protein, specifically aimed at restoring the function of the F508del mutant variant. This compound is particularly useful in cystic fibrosis research when used in combination with Tezacaftor and Ivacaftor, providing insights into pharmacological interventions for improving chloride ion transport in affected patients. Its role in potentiating drug efficacy makes it significant for developing combination therapies in the treatment of cystic fibrosis.
Chemical Information
| Catalog Num | A66501 |
|---|---|
| M. Wt | 630.74 |
| Formula | C28H32F3KN5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2204245-47-4 |
| Synonyms | VX-659 potassium |
| SMILES | O=C(C1=CC=C(N2N=C(OCCC3(C(F)(F)F)CC3)C=C2)N=C1N4C(C)(C)C[C@H](C)C4)NS(=O)(C5=CC=CC=C5)=O.[K] |
Biological Activity
| Description | Bamocaftor potassium is a CFTR corrector that targets the cystic fibrosis transmembrane conductance regulator (CFTR) protein, specifically aimed at restoring the function of the F508del mutant variant. This compound is particularly useful in cystic fibrosis research when used in combination with Tezacaftor and Ivacaftor, providing insights into pharmacological interventions for improving chloride ion transport in affected patients. Its role in potentiating drug efficacy makes it significant for developing combination therapies in the treatment of cystic fibrosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
