Product Data Sheet
1-Anthramine
Catalog No. A66508
1-Anthramine, also known as 1-aminoanthracene, acts as a fluorescent general anesthetic that enhances GABAergic transmission, exhibiting a binding affinity (Kd) of 0.1 mM to the general anesthetic site in horse spleen apoferritin (HSAF). Its fluorescent properties are significantly increased upon binding to HSAF, making it a valuable tool in research. Additionally, 1-Anthramine potentiates chloride currents induced by GABA and can reversibly inhibit the movement of Xenopus laevis, with an EC50 value of 16 μM, thus offering potential applications in neuroscience and anesthesiology studies.
Chemical Information
| Catalog Num | A66508 |
|---|---|
| M. Wt | 193.24 |
| Formula | C14H11N |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 610-49-1 |
| Synonyms | 1-Aminoanthracene |
| SMILES | NC1=CC=CC2=CC3=C(C=C12)C=CC=C3 |
Biological Activity
| Description | 1-Anthramine, also known as 1-aminoanthracene, acts as a fluorescent general anesthetic that enhances GABAergic transmission, exhibiting a binding affinity (Kd) of 0.1 mM to the general anesthetic site in horse spleen apoferritin (HSAF). Its fluorescent properties are significantly increased upon binding to HSAF, making it a valuable tool in research. Additionally, 1-Anthramine potentiates chloride currents induced by GABA and can reversibly inhibit the movement of Xenopus laevis, with an EC50 value of 16 μM, thus offering potential applications in neuroscience and anesthesiology studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
