Product Data Sheet

Ani9

Catalog No. A66512

main product photo
Ani9 is a selective inhibitor of the ANO1 chloride channel, exhibiting an IC50 of 77 nM. This compound effectively modulates smooth muscle contractions in murine models, making it a valuable tool for research on pathophysiological conditions such as tumors. Its inhibitory effects on chloride channels propose potential applications in studies targeting gastrointestinal disorders and related diseases.
Chemical Information
Catalog NumA66512
M. Wt332.78
FormulaC17H17ClN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.356102-14-2
Synonyms
SMILESO=C(COC1=CC=C(C=C1C)Cl)N/N=C/C2=CC=CC=C2OC
Biological Activity
DescriptionAni9 is a selective inhibitor of the ANO1 chloride channel, exhibiting an IC50 of 77 nM. This compound effectively modulates smooth muscle contractions in murine models, making it a valuable tool for research on pathophysiological conditions such as tumors. Its inhibitory effects on chloride channels propose potential applications in studies targeting gastrointestinal disorders and related diseases.
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