Lubiprostone (hemiketal)
Catalog No. A66533

Lubiprostone (hemiketal) is a selective activator of chloride channel 2 (CLCN2). It effectively increases chloride ion secretion in the intestine, enhancing fluid secretion and promoting intestinal peristalsis, making it valuable for studying chronic idiopathic constipation and opioid-induced constipation. This compound is also applicable in cancer research, providing insights into gastrointestinal function and potential therapeutic interventions.
Chemical Information
| Catalog Num | A66533 |
|---|---|
| M. Wt | 390.46 |
| Formula | C20H32F2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 333963-40-9 |
| Synonyms | RU-0211 (hemiketal); SPI-0211 (hemiketal) |
| SMILES | CCCCC(F)([C@@]1(O[C@@]2([H])[C@]([C@H](C(C2)=O)CCCCCCC(O)=O)([H])CC1)O)F |
Biological Activity
| Description | Lubiprostone (hemiketal) is a selective activator of chloride channel 2 (CLCN2). It effectively increases chloride ion secretion in the intestine, enhancing fluid secretion and promoting intestinal peristalsis, making it valuable for studying chronic idiopathic constipation and opioid-induced constipation. This compound is also applicable in cancer research, providing insights into gastrointestinal function and potential therapeutic interventions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


